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Medicinal cannabis or household painkillers?

Paracetamol, ibuprofen and aspirin. A common cupboard staple for that minor headache, and a popular fast-acting pain relief for multiple ailments. According to a survey featured in the Independent, Briton’s are taking an average of 373 per year! [1]

Yet, senior NHS officials disclose that aspirin, ibuprofen, paracetamol and opioids are all unsuitable for chronic primary pain. NICE declared that approximately 30-50% of the population may be affected by chronic pain and almost 50% of people with chronic pain also have a diagnosis of depression. While 66% of sufferers are unable to maintain full-time employment due to their condition. [2] These frightening statistics suggest you should think twice before regularly reaching for that box of painkillers.

As evidence increases regarding the risks of paracetamol, it has been shown to lower people’s sensitivity to hurt feelings, experiencing reduced empathy, and even affecting cognitive function. [3] These clinical trials based in the US show how our brains are developing long terms effects from using the household painkiller and the potential risks this can cause.

Paracetamol, an addictive drug?

The addictiveness of pain killers has more recently been exposed and has shown devastating effects for regular users. One of the most consumed drugs in the US – and the most commonly taken analgesic worldwide – could be doing a lot more than simply taking the edge off your headache, new evidence suggests. [4] University of Oxford announce how paracetamol use is associated with increased rates of death, heart attack, stomach bleeding and kidney failure. [5]

People have experienced great results from replacing common pain killers with medicinal cannabis. It contains little to no side effects and can help reduce pain by acting as a modulator of neural transmissions by binding with the CB1 receptors that form part of the endogenous cannabinoid system.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430692/

This is also the case in more serious chronic conditions, like rheumatoid arthritis.

COVID-19

Despite paracetamol being considered an essential medicine by the World Health Organisation, and recommended by the CDC as the primary drug you should take to ease mild symptoms of coronavirus [4] what many don’t know is the huge potential that CBD and THC – both prominent compounds found in medicinal cannabis have to offer to help treat pain, and may also act as a potential treatment for some of the complications that can arise in some severe cases of COVID-19.

In some cases, an aberrant immune response can lead to an overproduction of pro-inflammatory cytokines the resulting “cytokine storm” can harm the body’s tissues, such as lung tissue. This usually presents as diffuse alveolar damage in the case of lung-specific immunopathology. The immune cells start to attack healthy tissues blood vessels leak, blood pressure drops, clots form, and catastrophic organ failure can ensue. this can also lead to increased risks of stroke and neurological damage.

Medicinal cannabis can act as a partial agonist binding with the CB2 receptors and mediating the immune response, to either increase or reduce the production of pro-inflammatory cytokines. CB2 receptors are located in the endogenous cannabinoid system, these are expressed in cells distributed through the soft tissues and specifically the immune system and associated cells.
Many of us have sadly lost loved ones to the viral pandemic and as a consequence, the production of medicinal cannabis has a personal meaning for some in our company, which is why at our cultivation facility in Zimbabwe we have an active program in place to create proprietary genetic variants of cannabis that will be exclusively available to Eco Equity and its patients/pharmaceutical partners.

Whilst we work hard in producing a life-changing medicine we look forward to learning more about the scientific trials that may help fight the pandemic, which are taking place each day to uncover new therapies for a variety of chronic conditions.

Check out our scientific exploration of how cytokines play an important role in our immune system as signalling molecules and why should you care during the COVID-19 pandemic.
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