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Over 100 Cannabinoids Found In Cannabis But Which Are The Most Important?

The earliest evidence of cannabis originated in China during 4000 BCE in the form of pollen deposits. Cannabis was regarded among the ‘five grains’ and was farmed as a major food crop in addition to its major role in the production of textiles, rope, paper, and oil (hemp). [1] An extremely versatile plant that has many functional uses as well as medicinal.

Over time the acceptance of cannabis for medicinal and recreational purposes has seen some turbulent times concerning the ever-changing legalities across the globe. As of November 2018, medicinal cannabis was made legal in the UK.
Now in 2020, medicinal cannabis is legal in over 33 countries and further regions across the globe are following suit. Not only are these countries noticing the potential in cannabis as a medicine but also the financial value it can bring to the economy and investors due to the rapidly growing demand of consumers.
Cannabinoids
There is increasing evidence every year that more of the 144 known cannabinoids have therapeutic value and applications. There are also new cannabinoids being discovered annually.

A research team from Canada managed to find 21 new cannabinoids in 2018. This brought the total number to no less than 132 and according to some other resesrch groups there could be as many as 144 [2]

But which are the most important or hold most value? There are 3 key components that if you were an avid cannabis fan, you would most likely already heard of.

CBD

First discovered in 1940, CBD accounts for up to 40% of the plants extract [3] and unless you’ve been living on the moon for the past few years, you may have noticed CBD subtly appearing on the shelves of well-known high street stores, such as Holland&Barrett. CBD, is a medicinal compound of the plant and contains legally no more than 0.3% THC in any product available through retail (by law) and therefore has minimal psychoactive compounds that give you the recreational-high that many recreational cannabis users talk about.

At Eco Equity, medicinal cannabis is what we are cultivating and producing at our key site in Zimbabwe. We are forecasting initial annual production of approximately 15,470kg of EU-GMP cannabis flower, and 1,591Kg of EU-GMP Oil. This will be exported globally with a destination focus on Europe to help transform lives.

THC

Cannabis that has high THC content used to be considered one of the most commonly used illicit drugs in the world. [4] Although a lot of stigma is attached to this compound due to its recreational aspects mentioned, it does have huge therapeutic and medicinal value potential worth mentioning…

For example, it has been known to provide relief for similar ailments and conditions as CBD, such as pain management, glaucoma, insomnia, low appetite and nausea. [5]
 THC has therapeutic value in the treatment of cancer and the inhibition of tumor cell proliferation. [6]

We discovered in our recent blog how medicinal cannabis (specifically THC) can be used as a therapeutic remedy for cytokine storm (lung-specific immunopathology) in COVID-19 patients. You can learn more about this here!

The Entourage Effect
So what happens when both of these popular compounds come together?

Some research suggests that combining these compounds – along with smaller, organic compounds in the cannabis plant, known as terpenes or terpenoids — is more effective than taking CBD or THC alone. [7] Creating a more intense therapeutic effect. Scientific evidence of this is still in its infancy but is evolving by the day.

CBN

The CBN compound is commonly referred to as ‘the one that helps you sleep!’ – CBN can help tackle insomnia to provide you with a more restful sleep. CBN was actually the first cannabinoid to be identified by scientists [8] and it has been proven to be most effective in more maturely aged cannabis flowers.

Our Plans For Producing Effective Medicinal Cannabis

With the guidance from our expert team, including those with agricultural experience and years of formidable cannabis knowledge. Including our MD of Zimbabwe, Tommy Doran and Head of Cultivation Soheil Ghaffari we will be producing EU-GCAP (good manufacturing agricultural practice) to effectively produce medicinal cannabis that will make a difference and change the lives of many patients with chronic ailments. We pride ourselves on ensuring quality and continuing to expand our knowledge, one cannabinoid at a time.

If you enjoyed this blog and would like to read ‘What we learned about building a cannabis cultivation facility’, please click here!

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